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The remainder of the sequence corresponded to the 3'-region of the mRNA downstream from the terminationcodon.
2
Furthermore, the most C-terminally located premature terminationcodon mutation fails to rescue the progenitor cell proliferation defect in hippocampal slice cultures from Bcl11b-deficient mice.
3
RNA analysis revealed that an alternative splice site within exon 1 was used leading to a premature terminationcodon within exon 2.
4
Affected animals carry a mutation that predicts a premature terminationcodon in exon 8 and a peptide that is 5% the size of normal dystrophin.
5
Due to premature terminationcodons, none encodes functional protein.
Usage of stop codon in English
1
However, the stopcodon is preceded by a run of 11 consecutive adenosines.
2
The single-base pair mutation causes a frameshift, which results in premature stopcodon.
3
This duplication results in a frame shift and premature stopcodon.
4
A premature stopcodon UGA appeared to be most responsive to PTC124 treatment.
5
The 5'UTR contains two false AUG initiation codons followed by a stopcodon.
6
One variant introduces an early stopcodon in MLL3, which predicts complete loss-of-function.
7
On exposure to cre-recombinase a stopcodon is generated immediately downstream in exon 6.
8
This bias near the stopcodon is partially release-factor specific.
9
One WP sequence with an HBx stopcodon suggested infectivity.
10
Addition of Sec into a protein is achieved by recoding of the UGA stopcodon.
11
Most RS-exons contain a premature stopcodon such that their inclusion can decrease mRNA stability.
12
The first variant generates a premature stopcodon (NCBI accession no.
13
In all these transcripts the open reading frame is maintained until the same stopcodon.
14
No correlation was found between the spermiogram and the changes leading to the stopcodon.
15
Tryptophan acts by inhibiting Release Factor 2-mediated cleavage of this peptidyl-tRNA at the tnaC stopcodon.
16
Additionally, stopcodon-gain variants in two intronless genes were not expressed, an unexpected outcome given previous studies.